Beneficial Microbes: The pharmacy in the gut.

In the past few years the relationship between scientific evidence supporting the maintenance and health maintenance of the intestinal flora and various pathologies metabolized to mental health has dramatically increased. An aggressive regulatory strategy addressing microbiome function related to these diseases is a great possibility for the food and pharmaceutical industry to provide innovative and therapeutic solutions to many health problems affecting modern society Provide sex. These strategies may include the use of probiotics and prebiotics as nutritional supplement therapies. Probiotics is considered a good treatment for preventing harmful intestinal microorganisms, helping digestion and nutrient absorption, and contributing to immune function. Probiotics has been reported to improve intestinal microbial balance and promote return to baseline microbial community after disability events such as antibiotic treatment (ecological disorder). Prebiotics are selective fermentation components that can make specific alterations in the composition and / or activity of the gastrointestinal flora to confer health and health benefits to the host.

The intake of probiotics, prebiotics and microencapsulated nutrients, beneficial molecules or microorganisms will provide a health benefit to the body by increasing the number of beneficial microorganisms or their products and intestines It is aiming. There is a need to know further which microorganisms and functions are beneficial for effectively cultivating, delivering and / or stimulating the growth of appropriate microorganisms. Currently, there are very few intestinal microorganisms in adults used to assess the effect of diet therapy (including prebiotics) on the health of the probiotics or gastrointestinal tract.

How is intestinal microorganism related to this? Believe it or not, our intestinal microorganisms also have a circadian rhythm. Many types of intestinal microorganisms vibrate during the day and at night during activity and concentration. For example, intestinal bacterial enterobacteria are sensitive to melatonin ("sleeping" hormone). It is usually found in our intestines, plays a role in fermenting sugar and generating gas. It may also cause opportunistic infections as it spreads to other tissues, or when its relative abundance increases for antibiotic therapy.

Obviously, intestinal microorganisms are sensitive to local environmental changes. But this relationship is not a unilateral dictation - it is a conversation. Microorganisms in our intestines may also grasp the reins and affect the ability of the body to maintain homeostasis. This is especially true when examining the gap between the bowel clock and the brain's clock. For example, when igniting intestinal microorganisms late at night, when they are ready to sleep instead of food they may adversely affect fat metabolism and weight gain. For those with a change in appetite due to jet lag, it is not surprising that traveling through contradictory sleep times and time zones increases the risk of obesity, fat retention, and metabolic disorders such as type 2 diabetes. In fact, when we transfer intestinal microorganisms of jet lag to mice, we gain weight soon.