Aplastic anemia is a disease that stops the body from producing enough new blood cells. This disease can make you very tiring, it may make it more susceptible to infections and uncontrollable bleeding. This rare and serious illness can develop at any age. Aplastic anemia may occur suddenly or slowly over time. This disease may be short-lived, but in some cases it may be a chronic illness that may be fatal.
Aplastic anemia occurs when the bone marrow is damaged and the production of new blood cells slows or stops. The bone marrow is a red spongy substance in the bone that produces stem cells that produce other cells. Bone marrow stem cells produce blood cells such as red blood cells, white blood cells, and platelets. In aplastic anemia, the bone marrow is medically described as a mal-regenerative disease. In other words, the bone marrow is empty or contains little blood cells (Mayo Clinic 2014).
Factors that may temporarily or permanently damage the bone marrow and affect blood cell formation include the following.
Treatment of Radiation and Chemotherapy These anti-cancer therapies kill cancer cells but also destroy healthy cells including bone marrow stem cells. Aplastic anemia may be a temporary side effect of these treatments
Contact with toxic chemicals. Exposure to toxic chemical substances such as toxic chemical substances used for pesticides and pesticides may cause aplastic anemia. Also associated with aplastic anemia - exposure to benzene - gasoline components. This type of anemia may improve yourself if you avoid repeated exposure to chemicals that are causing the first disease.
Use a specific medicine. Some drugs, such as those used for the treatment of rheumatoid arthritis and antibiotics, can cause aplastic anemia.
Autoimmune diseases Autoimmune diseases in which the immune system begins to attack healthy cells may include bone marrow stem cells
Virus infection Viral infections affecting the bone marrow may be involved in the development of aplastic anemia in some people. Viruses associated with the development of aplastic anemia include hepatitis, Epstein Bar, Cytomegalovirus, Parvovirus B 19 and HIV
Aplastic anemia that occurs during pregnancy during pregnancy may be related to autoimmune problems - your immune system may attack your bone marrow during pregnancy
Unknown factors In many cases, the doctor can not determine the cause of aplastic anemia. this is
There is no bone tenderness (Mc Phee 454). The cause of aplastic anemia occurs when the bone marrow is damaged or in some cases unknown. Approximately 75 out of 100 acquired aplastic anemia were atypical (aplastic anemia MDS International Foundation, Inc.). This means they have no known reason. In some cases, cases may come from radiation therapy or cancer chemotherapy. This destroys healthy cells in the bone marrow, leading to secondary illness. Other causes of secondary aplastic anemia secondary diseases are toxic chemicals and certain drugs such as chemical benzene in gasoline or the use of certain medicines including chloramphenicol, carbamazepine, felbamate, phenytoin is. Quinine and Bao Taisong (Wikipedia)) There were less than 1 abnormality occurred in 40,000 treatments after chloramphenicol treatment, and carbamazepine was weakened or even rare (Wikipedia)
In aplastic anemia, the bone marrow significantly reduces the production of all kinds of blood cells (red, white, platelets). Reproduction failure means "development failure" in reality. Acute or chronic aplastic anemia is a rare and serious disease that can occur spontaneously or by certain drugs or toxins. Most of the causes of aplastic anemia are unknown. Certain cancer treatments such as high-dose chemotherapy and radiotherapy can cause aplastic anemia. Other possible causes include chemicals (such as benzene), a variety of marketed drugs and prescription drugs (such as infectious diseases, cancer, seizures, drugs used in the treatment of arthritis, etc.), viruses (such as parvovirus B 19) There are immune diseases (such as hepatitis). Or, HIV, pregnancy, drugs on the street or environmental toxins (pesticides, pesticides etc). Fanconi anemia is a hereditary disease
What are the anatomical and physiological symptoms and causes of aplastic anemia? What is the diagnosis and treatment of aplastic anemia? One symptom is fatigue due to anemia. Anemia is when blood levels of erythrocytes are low. Red blood cells carry oxygen from the lungs to various parts of the body (aplastic anemia and MDS International Foundation, Inc.). This can cause fatigue when the body does not get enough oxygen. Aplastic anemia cells contain only a few red cells