Antiseptic barrier cap effective in reducing central line-associated bloodstream infections: A systematic review and meta-analysis.

Erasmus MC Neonatal Pediatrics - Sofia Children's Hospital, Rotterdam, the Netherlands

Erasmus MC Obstetrics and Gynecology - Sofia Children's Hospital, Rotterdam, the Netherlands

Utrecht University Medical Center, Wilhelmina Children's Hospital, Clinical Health Sciences, University of Utrecht, The Netherlands

Erasmus MC Intensive Care Unit - Sofia Children's Hospital, The Netherlands, Rotterdam. Electronic address: w.ista@erasmusmc.nl

Microorganisms can enter the central venous catheter through the catheter cannula lumen. The catheter cannula should be properly sterilized to prevent blood flow infection (CLABSI) associated with the centerline. However, there are few manual manual disinfection procedures that take time. Another way is to use an anti-corrosive cap to clean the catheter cannula by continuous passive disinfection.

Compare the effect of using anticorrosion barrier cap versus manual disinfection against CLABSI incidence

Until May 10, 2016, we searched systematically Embase, Medline Ovid, Web-of-Science, CINAHL EBSCO, Cochrane Library, PubMed Publisher and Google Scholar. The main result was a decrease in CLABSI per 1000 catheter days, expressed as incidence ratio (IRR), analyzed using random effect meta-analysis. 2) use an antibacterial barrier cap for the centerline hub to enter the bloodstream, 3) report the number of CLABSI per 1000 catheter days when using the manual cap with the barrier cap when conducting research in the hospital environment To include research. Disinfection

After the exclusion was repeated, 953 papers were selected based on the title and abstract, and 18 papers were completely read. Finally, nine studies were included in the systematic review, seven of which were included in the meta-analysis of the random effects. Combined IRR showed that the use of antimicrobial barrier caps can effectively reduce CLABSI (IRR = 0.59, 95% CI = 0.45 - 0.77, P <0.001)

The use of antimicrobial barrier caps is associated with a decrease in the incidence of CLABSI and is a valuable intervention to add to the bundle of centerline maintenance therapy

Corrosion barrier cap, centerline related bloodstream infection, infection control, meta-analysis, systematic review

The following inclusion criteria were used: 1) Studies conducted in hospital environment; 2) Anti-corrosion barrier cap for centerline center to enter the bloodstream; 3) Per capillary days per 1000 days of manual disinfection Antibacterial barrier cap for reporting CLABSI. Exclusion criteria are as follows: 1) Comment - However, to manually search references to comments on CLABSI's prevention to determine other studies; 2) Studies on barrier caps for feeding tubes or blood 3) a summary of the meeting, a letter and summary to the editor; 4) lack of CLABSI information research per 1000 catheter days after contact with the corresponding author. These inclusion and exclusion criteria are used to select articles based on titles and abstracts and to select articles based on full text.

Antimicrobial barrier caps are effective in reducing centerline related bloodstream infections: systematic review and meta-analysis

BACKGROUND: Microorganisms can enter the central venous catheter from the catheter cannula lumen. The catheter cannula should be properly sterilized to prevent blood flow infection (CLABSI) associated with the centerline. However, there are few manual manual disinfection procedures that take time. Another way is to use an anti-corrosive cap to clean the catheter cannula by continuous passive disinfection. Objective: To compare the effect of anti-corrosion barrier cap and manual disinfection against the incidence of CLABSI. Design: Systematic review and meta-analysis. METHODS: By May 10, 2016, we searched systematically Embase, Medline Ovid, Web-of-Science, CINAHL EBSCO, Cochrane Library, PubMed Publisher and Google Scholar. The main outcome was a decrease in CLABSI per 1000 catheter days, expressed as an incidence ratio (IRR), analyzed using a random effect meta-analysis

Antimicrobial barrier caps are effective in reducing centerline related bloodstream infections: systematic review and meta-analysis